Description
Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-:-Ile-5' bond of angiotensin I and the 'Phe-20-:-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-:-His-9' bond of angiotensin I and the 'Phe-4-:-Ala-5' and 'Tyr-10-:-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing